Marc Foretz Selected Research

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)

1/2019

Phenformin, But Not Metformin, Delays Development of T Cell Acute Lymphoblastic Leukemia/Lymphoma via Cell-Autonomous AMPK Activation.

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Marc Foretz Research Topics

Disease

17	Insulin Resistance 10/2023 - 01/2004
13	Type 2 Diabetes Mellitus (MODY) 01/2023 - 09/2008
9	Obesity 10/2023 - 09/2012
9	Neoplasms (Cancer) 01/2023 - 07/2006
9	Inflammation (Inflammations) 01/2022 - 03/2011
6	Hyperglycemia 11/2020 - 05/2005
5	Fatty Liver 01/2024 - 05/2005
4	Body Weight (Weight, Body) 05/2024 - 04/2015
4	Hypoxia (Hypoxemia) 10/2021 - 07/2006
4	Hypoglycemia (Reactive Hypoglycemia) 11/2020 - 05/2005
4	Starvation 09/2020 - 08/2011
4	Hypertrophy 02/2012 - 04/2006
3	Metabolic Diseases (Metabolic Disease) 01/2024 - 05/2017
3	Heart Failure 01/2023 - 01/2014
3	Non-alcoholic Fatty Liver Disease 01/2022 - 01/2018
3	Cardiovascular Diseases (Cardiovascular Disease) 12/2021 - 12/2014
3	Hepatocellular Carcinoma (Hepatoma) 07/2020 - 12/2006
2	Disease Progression 05/2024 - 01/2022
2	Fibrosis (Cirrhosis) 05/2024 - 07/2020
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 06/2011
2	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 01/2022 - 03/2012
2	Atherosclerosis 12/2020 - 01/2015
2	Necrosis 09/2020 - 12/2018
2	Infections 12/2017 - 03/2015
2	Diabetes Mellitus 08/2016 - 02/2013
2	Left Ventricular Dysfunction 08/2016 - 12/2013
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 06/2015 - 11/2010
2	Splenomegaly 09/2014 - 01/2011
2	Anemia 09/2014 - 08/2010
2	Hyperinsulinism (Hyperinsulinemia) 05/2006 - 01/2004
1	Alcoholic Fatty Liver 05/2024
1	Autistic Disorder (Autism) 03/2024
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 01/2023
1	Chronic Renal Insufficiency 01/2023
1	Hypercalcemia (Milk Alkali Syndrome) 01/2023
1	COVID-19 01/2023
1	Chronic Kidney Disease-Mineral and Bone Disorder (Renal Rickets) 01/2023
1	Dyslipidemias (Dyslipidemia) 01/2022
1	Pulmonary Hypertension 01/2022
1	Amyloid Plaque 01/2022
1	Infertility (Sterility) 01/2022
1	Adenocarcinoma of Lung 01/2022
1	Colitis 01/2022
1	Alzheimer Disease (Alzheimer's Disease) 01/2022
1	Atrial Fibrillation 01/2022
1	Osteoporosis 01/2021
1	Bone Resorption 01/2021
1	Sarcopenia 11/2020
1	Cachexia 11/2020
1	Neuroblastoma 09/2020
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2019

Drug/Important Bio-Agent (IBA)

22	Glucose (Dextrose)FDA LinkGeneric 01/2024 - 01/2004
19	AMP-Activated Protein KinasesIBA 05/2024 - 05/2005
17	Metformin (Glucophage)FDA LinkGeneric 05/2024 - 02/2007
13	Insulin (Novolin)FDA Link 10/2021 - 01/2004
9	LipidsIBA 12/2020 - 05/2005
7	Phosphotransferases (Kinase)IBA 03/2024 - 01/2009
4	Mechanistic Target of Rapamycin Complex 1IBA 01/2019 - 08/2011
3	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2021 - 09/2014
3	Adenosine Monophosphate (AMP)IBA 09/2020 - 12/2013
3	TOR Serine-Threonine KinasesIBA 09/2020 - 11/2010
3	Glucagon (Glukagon)FDA Link 01/2020 - 12/2005
3	Protein Isoforms (Isoforms)IBA 10/2018 - 04/2006
3	Oxygen (Dioxygen)IBA 10/2018 - 07/2006
3	Proteins (Proteins, Gene)FDA Link 12/2017 - 02/2007
3	AICA ribonucleotide (ZMP)IBA 01/2017 - 02/2007
2	SaltsIBA 10/2023 - 01/2021
2	LipopolysaccharidesIBA 10/2021 - 12/2013
2	Amino Acids FDA Link 11/2020 - 09/2020
2	Protein Kinases (Protein Kinase)IBA 07/2020 - 12/2013
2	BiguanidesIBA 01/2019 - 11/2010
2	Angiotensin IIIBA 01/2019 - 12/2018
2	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 01/2019 - 09/2012
2	CytokinesIBA 12/2018 - 08/2016
2	LigandsIBA 08/2016 - 01/2015
2	Sirtuin 1IBA 03/2015 - 03/2010
2	GlycogenIBA 06/2014 - 01/2004
2	Peptide Elongation Factor 2 (EF-2)IBA 07/2009 - 02/2007
1	CollagenIBA 05/2024
1	Glutamine (L-Glutamine)FDA Link 01/2023
1	25-Hydroxyvitamin D3 1-alpha-Hydroxylase (25 Hydroxyvitamin D3 1 alpha Hydroxylase)IBA 01/2023
1	MineralsIBA 01/2023
1	PotassiumIBA 01/2022
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2022
1	Dextrans (Dextran)FDA Link 01/2022
1	2- chloro- 3- (1- hydroxy- 5,6,7,8- tetrahydronaphthalen- 2- yl)- 6- oxo- 5- phenyl- 7H- thieno)(2,3- b)pyridin- 4- olate potassiumIBA 01/2022
1	Amyloid (Amyloid Fibrils)IBA 01/2022
1	Adrenergic Agents (Adrenergic Drugs)IBA 10/2021
1	YKL-05-099IBA 01/2021
1	4- hydroxy- 3- (4- (2- hydroxyphenyl)phenyl)- 6- oxo- 7H- thieno(2,3- b)pyridine- 5- carbonitrileIBA 12/2020
1	Hormones (Hormone)IBA 11/2020
1	Beclin-1IBA 09/2020
1	Adenosine Triphosphate (ATP)IBA 09/2020
1	Glutamic Acid (Glutamate)FDA Link 09/2020
1	FructoseIBA 07/2020
1	CholesterolIBA 07/2020
1	Adenylate KinaseIBA 01/2020
1	Phenformin (Fenformin)IBA 01/2019

Therapy/Procedure

8	Therapeutics 05/2024 - 01/2009
1	Immunotherapy 01/2022